Endocrine Abstracts

Background: The relationship between obesity, metabolic traits and adrenal incidentaloma (AI) in clinical studies have been discussed mainly in one direction: as the consequences of mild autonomous cortisol secretion in autonomous cortisol secreting AI (ACS) and as possible consequences of minimal hormonal secretion not detectable by current diagnostic methods in non-functioning (NF) AI. However, the observed anabolic and mitogenic effects of insulin on adrenal cortex from pre...

Background: Pheochromocytomas (PHEO) and paragangliomas (PGL) are rare neuroendocrine tumors that can lead to life-threatening conditions. The diagnosis of PHEO/PGL is established by measuring normetanephrine and metanephrine. Biochemical detection usually precedes clinical diagnosis of PHEO/PGL by several years. Co-occurrence of cyanotic congenital heart disease (CCHD) and PHEO/PGL has been reported but potential association remains unclear. We aimed to compare plasma metanep...

ObjectiveThere are few data on long-term follow-up of patients with nonfunctioning adrenal incidentalomas (NFAIs). We aimed to determine the natural history of NFAI at 10 year follow-up. We also evaluated the associations between baseline body mass index (BMI) and changes of NFAIs’ and patients’ characteristics at follow-up period.DesignLongitudinal observational study.Patient...